.Nature Medicine, Published online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and epidemiologic studies exposed that an unfamiliar reassortant virus-like family tree of the Oropouche infection, which has actually been spreading in the western side Amazon area of Brazil for concerning a years, is actually connected with the recent human outbreaks between 2022 and 2024.